Instructions for Use

How to Use Amuse

Your complete guide to safely introducing allergens with Amuse Daily Drops—from your first dose to daily routines

Before You Give the First Dose

Let’s make sure you and your baby are ready. Take a moment to go through this quick checklist.

Check Baby's Readiness

Baby is at least 2 months old, healthy today (no fever, illness, or new rash), and has been tolerating milk feeds well.

Pick Your Time

Choose a time when you can watch baby for 1-2 hours after the first dose. Daytime is ideal when help is easily accessible if needed.

Talk to Your Doctor

If baby has moderate-to-severe eczema, a sibling with food allergies, or you have concerns, consult your pediatrician first.

Let's Give Your First Dose

You’ve got this! Here’s exactly what to do, step by step. Take your time—there’s no rush.

Prep Your Bottle

Shake the bottle well. This mixes all 6 allergens evenly so each drop has exactly what your baby needs.

First bottle tip: Check the expiration date on the bottom of the bottle and mark today’s date on the label. Active bottles are good for 30 days once opened. Keep any unopened bottles in the refrigerator until ready for use!

Choose Your Starting Dose

A full dose is 3 pumps (0.42mL), but for your very first time, you have options.

You can start with 3 pumps if you’re feeling confident and baby has no risk factors; or start with 1-2 pumps if you want to ease in, then build up to 3 over the next few days.

Our recommendation: There is no right or wrong way to get started.  It’s most important that you maintain consistency with daily dosing.

Position & Pump

When your baby is calm (after a diaper change!), gently place the pump tip in their mouth, then:

1) Hook the tip over the lower gums, aiming under the tongue if possible

2) Press the pump slowly—once, twice, three times

3) The liquid will go directly onto the oral mucosa (that’s where the magic happens!)

If baby spits it out: Totally normal! Wipe their face clean. The important exposure already happened the moment the drops touched their mouth. You can try again later if you want or the following day.

Watch & Relax

You did it! Now you can go about your day, just keeping an eye on baby for the next 1-2 hours. While reactions are rare at these microdose levels, here’s what to watch for:
     
  • Hives, rash or facial swelling
  •  
  • Vomiting or difficulty breathing
  •  
  • Unusual fussiness or refusal to feed

Most likely scenario:Baby acts totally normal. Maybe they made a funny face at the new taste, but that’s about it. After this first dose, you’ll feel much more confident going forward!

Building Your Daily Routine

After that first dose, here’s how to make Amuse a seamless part of your day

Pick Your Daily Time

Same time every day helps build the habit. Popular choices: after morning feed, during diaper change, or before bedtime. Whatever works for your family!

Set a Daily Reminder

Life gets busy! Set a phone reminder for your chosen time. After 2-3 weeks, it’ll become second nature and you won’t need it.

Store Properly

Keep unopened bottles in the fridge. Once opened, store at room temperature in a cool, dry spot away from sunlight

Mark Your Calendar

Write today’s date on your bottle label. Toss it after 30 days and start a fresh one—even if there’s liquid left.

Missed a Day?

No stress. Just pick up where you left off tomorrow. Consistency over time matters more than perfection. You’re doing great!

Talk to Your Pediatrician

Let your doctor know you’ve started Amuse at your next visit. They’ll likely be supportive—early introduction is now recommended!

What to Expect (And What to Watch For)

Reactions are rare at these microdose levels, but here’s what you should know

Normal vs. Concerning

Most babies: Act completely normal. You might see minor things like slightly softer stools or temporary redness around the mouth—this is fine and similar to any new food introduction.
Stop use and call your doctor if you see:

Hives or rash on body

Swelling of lips, tongue or face

Vomiting

Difficulty breathing or wheezing

Severe persistent fussiness

Complete refusal to feed

Emergency Symptoms: If you see multiple symptoms at once or any difficulty breathing, call 911 immediately.

When to pause or not start

Baby is sick: Wait until they’re healthy. No fever, no illness, no new rashes (eczema is ok)

History of severe food reactions: Talk to your allergist first before starting

Feeding difficulties or health concerns: Consult your pediatrician before beginning

You have questions or feel uncertain: Reach out to us or your doctor. We’re here to help you feel confident!

What's Inside Each Dose

Amuse provides safe, gentle exposure to 6 top allergens— naturally.

Peanut

sesame

cashew

walnut

Milk

Egg

Peanut

walnut

sesame

cashew

Milk

Egg

That’s It—Just 7 total ingredients

Six allergen proteins + Glycerin (a natural preservative). No artificial colors, flavors or unnecessary additives.

Questions?

We have answers.

Give your baby Amuse in 3 easy steps:

Step 1: Shake the bottle well for 5-10 seconds

Step 2: Gently insert the tip of the bottle into baby’s mouth, ideally under baby’s tongue to encourage swallowing.

Step 3: Press the pump 3 times for a complete dose (0.42mL total). The drops have a mild, slightly sweet taste that most babies tolerate well.


That’s it! Your baby’s developing immune system will take it from there. What’s most important is finding a consistent routine that allows for frequent exposure to these allergens.

Pro tip: Administer after a feeding when baby is calm and content. Some parents find it easiest during a diaper change when baby is lying down.

Ready to begin? 

Good news—swallowing isn’t necessary! 

Even if baby spits out some of the liquid after you administer it, the allergen proteins have already made contact with the immune cells in the mouth. Don’t worry about giving an extra dose to “make up” for spit-out drops.

Anytime that works consistently for your routine! Some popular options include:

After morning feeding: When baby is usually calm and happy

Before bedtime: Drops become part of the evening routine

During diaper changes: baby is already lying down and Amuse can be a fun distraction


The most important thing is picking a time you can stick with daily. Consistency is what matters the most!

Don’t stress! Just resume the next day with the regular dose. Missing an occasional day won’t derail the process—sustained exposure over time is what matters, not perfection.

If you miss several days in a row, simply pick back up where you left off. There’s no need to “catch up” by giving extra doses.
We recommend continuing Amuse until your child regularly eats all six allergens in whole food form, typically around 2-3 years old.

The transition: Once your child is eating peanut butter, tree nuts, eggs, sesame, and dairy regularly (several times per week), you can gradually discontinue Amuse.

Many families continue Amuse alongside solid food introduction during the 6-24 month period, then phase out as their child’s diet becomes more varied.
Yes! Amuse can complement other introduction methods. Many families follow a schedule like this:

Amuse (2-6 months): Early allergen exposure before solid foods

Amuse + food-based products (6+ months):Guarantees allergen exposure while baby is introduced to table foods

Amuse + whole foods (8+ months) Continued use of Amuse drops alongside table foods until baby is consuming these allergens on a regular basis (2-3x per week)

Unopened bottles: Unopened bottles of Amuse should be stored in the refrigerator until ready for use. Refrigeration helps maintain the protein potency in the drops.

Open bottles: Opened bottles should be stored at room temperature in a cool, dry place away from direct sunlight. No refrigeration needed! Keep the cap tightly closed when not in use. Each bottle has a 12-month shelf life from the manufacturing date (check the expiration date on your bottle).

You can stop using Amuse at any time—but it’s important not to stop allergen exposure entirely. The protective effect of early introduction only lasts as long as your child continues eating these foods regularly.

Here’s what to do when you discontinue Amuse:

Transition to whole foods: Start introducing these allergens through regular foods as early as your baby is developmentally ready. Ideally, your child should be eating all six allergens (peanut, tree nuts, eggs, sesame, milk, and dairy products) by 12 months.

Maintain consistent exposure: Once you stop Amuse, aim for approximately 2 grams of protein from each allergen at least 3 times per week. Two grams of protein from each allergen is roughly:

  • 2 teaspoons of peanut butter
  • 1 egg
  • 4 ounces of milk or yogurt
  • 1 tablespoon of tahini (sesame)
  • Small handful of tree nuts (or 2 tablespoons nut butter)

Why it matters: Food allergies are most likely to develop in the first 3 years of life. Consistent exposure during this critical period—whether through Amuse or whole foods—is your best protection. Gaps in exposure can allow sensitization to occur.

The bottom line: Amuse is a tool to start early and stay consistent. Once your child is eating these foods regularly as part of their normal diet, Amuse has done its job—just make sure the allergen exposure continues through food.

That said, many families continue using Amuse well into toddlerhood for foods their child refuses to eat. Continuing Amuse ensures they still get consistent exposure to those proteins.  Since they’re already familiar with the drops, it’s often easier than battling food preferences during the critical first 3 years when allergies are most likely to develop.

Amuse is designed to be safe for most infants starting at 2 months. Our microdosing protocol uses protein volumes well below typical reaction thresholds. However, we recommend consulting your healthcare provider before starting if your baby has existing allergies, severe eczema, or significant family history of allergies.

Safety by design: Research suggests that sensitization to common food allergens can begin early—often before solid foods are introduced. Starting during this window helps support immune system education before sensitivities may develop.

Each daily dose (3 pumps = 0.42mL) contains precise volumes of purified protein extract per allergen. This microdose range is:

  • Well below reaction thresholds (typical reactions occur at 100+ mg)
  • Sufficient for immune exposure based on sublingual immunotherapy research
  • Precisely measured through our pump delivery system

  • All six allergens (peanut, cashew, walnut, sesame, egg white, milk) are present in every bottle.

    While reactions to our microdoses are extremely rare due to the low amounts, it’s good practice to monitor your baby after the first few doses. Watch for symptoms like the ones listed below. If you notice any concerning symptoms, stop use immediately and contact your pediatrician or call 911.

    Hives or rash

    Swelling of the lips, face, or tongue

    Vomiting or diarrhea

    Difficulty breathing or wheezing

    Excessive fussiness or discomfort

    First dose tip: Administer the first dose when you’re able to monitor your baby for 1-2 hours, preferably during daytime hours when medical help is easily accessible.

    While we recommend sticking to the 3-pump daily dose for consistency, accidentally giving 4-5 pumps on occasion is not dangerous. Our doses are designed with safety margins well below reaction thresholds.

    However, don’t intentionally give more than the recommended dose—more is not better for building tolerance, and consistency at the recommended amount is what matters most.

    Every single batch of Amuse undergoes comprehensive third-party testing for:

    • Safety: Microbial testing to ensure no harmful bacteria or contaminants
    • Stability: Verifying the formula maintains its effectiveness throughout shelf life
    • Accuracy: Confirming precise allergen protein concentrations

    We maintain certificates of analysis for all testing and manufacture in a GMP-certified facility that follows strict FDA guidelines.

    Have more questions? Explore all of our FAQs.

    We're Here If You Need Us

    Seriously. Whether you have a question at 2pm or 2am, or you just want reassurance you’re doing it right—reach out. We’ve been there, and we’re here to help.

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